Weed Killer That Won't Kill St Augustine Grass

St Augustine lawns are beautiful but sensitive. Learn which selective herbicides control weeds without harming your grass, how to apply them safely, and what to avoid.

Quick Answer: The safest weed killers for St Augustine grass are selective post-emergent herbicides containing 2,4-D, dicamba, MCPP, or atrazine (where permitted). Always verify the product label explicitly lists St Augustine as a tolerant turfgrass before applying.

Why St Augustine Grass Is So Sensitive to Weed Killers

St Augustine grass (Stenotaphrum secundatum) is a warm-season turfgrass prized for its thick, broad blades and lush green carpet. It thrives in southern climates and is a favorite for homeowners who want a low-maintenance, heat-tolerant lawn. However, St Augustine is also one of the most herbicide-sensitive turfgrasses available. Its broad leaves absorb chemicals more readily than fine-bladed grasses like Bermuda or fescue, making it vulnerable to non-selective or improperly applied products.

This sensitivity means you cannot simply grab any weed killer off the shelf. Using a non-selective herbicide like glyphosate will kill your St Augustine grass just as effectively as it kills the weeds. Even some selective products formulated for other grass types can cause yellowing, stunting, or death in St Augustine lawns. Understanding the difference between selective and non-selective herbicides is the first step toward protecting your lawn while eliminating weeds.

If you are also managing other lawn care tasks, such as maintaining a healthy watering schedule or choosing the right weed and feed for St Augustine grass, combining those practices with a safe herbicide strategy will give you the best results.

Selective vs. Non-Selective Weed Killers

Weed killers fall into two broad categories: selective and non-selective. Selective herbicides are designed to target specific types of plants (like broadleaf weeds or certain grasses) while leaving the desired turfgrass unharmed. Non-selective herbicides, such as glyphosate, kill virtually all plants they contact, including your lawn.

For St Augustine grass, you must use a selective herbicide that is explicitly labeled as safe for this grass type. Even within selective herbicides, not all products are safe for St Augustine. Some broadleaf weed killers are formulated for cool-season grasses and can damage warm-season turf. Always read the label and confirm that St Augustine grass appears in the list of tolerant turfgrasses.

If you are dealing with weeds in other areas of your landscape, such as flower beds or vegetable gardens, you may need different products. For example, a weed killer for flower beds that won't kill plants is formulated differently than a lawn herbicide. Similarly, if you have pets, consider a pet-safe weed killer that won't kill grass to minimize risks.

Safe Active Ingredients for St Augustine Grass

The following active ingredients are commonly found in selective herbicides labeled as safe for St Augustine grass. Each has a specific mode of action and target weed spectrum. Always confirm the individual product label before use.

1. 2,4-D (2,4-Dichlorophenoxyacetic acid)

2,4-D is one of the most widely used broadleaf herbicides in lawn care. It targets broadleaf weeds like dandelions, clover, and plantain while leaving grasses largely unaffected. Many three-way broadleaf herbicides combine 2,4-D with dicamba and MCPP for a broader spectrum of control. When formulated for St Augustine, 2,4-D products can be effective and safe if applied at the correct rate and timing.

2. Dicamba

Dicamba is another broadleaf herbicide often used in combination with 2,4-D and MCPP. It is effective against tough weeds like chickweed and knotweed. Dicamba can be absorbed by roots, so apply carefully to avoid runoff into desirable plants. Products labeled for St Augustine typically use lower concentrations to minimize turf injury.

3. MCPP (Mecoprop-p)

MCPP is a broadleaf herbicide that works well on clover, dandelion, and other common lawn weeds. It is often included in three-way herbicide blends. Like the other ingredients, MCPP should only be used in products specifically labeled for St Augustine grass.

4. Atrazine

Atrazine is a selective herbicide that controls both broadleaf and grassy weeds in St Augustine lawns. It is particularly effective against crabgrass and other annual grasses. However, atrazine is regulated in many areas and may not be available in all regions. Check local regulations before purchasing or applying atrazine-based products. It should not be used on newly sodded or sprigged lawns until the grass is well established.

5. Quinclorac

Quinclorac is effective against crabgrass and other grassy weeds, but it is not universally safe for St Augustine. Some formulations can cause injury, especially during hot weather or on stressed lawns. Only use quinclorac products that explicitly list St Augustine as tolerant, and follow application instructions precisely.

Pro Tip: Three-way broadleaf herbicides (2,4-D + dicamba + MCPP) are among the most reliable selective options for St Augustine lawns. Look for products labeled "for St Augustine grass" and apply when weeds are actively growing and temperatures are moderate.

Comparison of Safe Herbicide Options

The table below summarizes the most common selective herbicide active ingredients and their suitability for St Augustine grass. Remember that product formulations vary, so always check the label.

Active Ingredient Target Weeds St Augustine Safety Notes
2,4-D Broadleaf weeds (dandelion, clover, plantain) Safe when labeled for St Augustine Often combined in three-way blends; avoid drift to sensitive plants
Dicamba Broadleaf weeds (chickweed, knotweed) Safe when labeled for St Augustine Root uptake possible; avoid runoff
MCPP Clover, dandelion, broadleaf weeds Safe when labeled for St Augustine Common in three-way herbicide blends
Atrazine Broadleaf and grassy weeds (crabgrass) Safe when labeled for St Augustine Regulated in some areas; not for new sod
Quinclorac Crabgrass and grassy weeds Use only products labeled for St Augustine Can cause injury in heat; apply with caution
Glyphosate (non-selective) All plants Not safe — will kill St Augustine Only for spot treatment far from lawn or with shielded applicator

How to Apply Weed Killer Safely to St Augustine Grass

Even the right product can cause damage if applied incorrectly. Follow these best practices to protect your lawn while effectively controlling weeds.

Timing Is Critical

Apply selective herbicides when weeds are actively growing and temperatures are between 65°F and 85°F. Avoid application during heat waves, drought, or when the lawn is dormant. St Augustine grass is most vulnerable to herbicide injury during transition periods (spring green-up and fall dormancy). Early morning or late afternoon application reduces evaporation and drift.

Do Not Apply to Stressed Grass

If your lawn is suffering from drought, disease, insect damage, or recent mowing, wait until it recovers before applying weed killer. Stressed grass is more susceptible to herbicide injury. Similarly, do not apply to newly sodded or sprigged lawns until the grass is well rooted and established.

Calibrate Your Sprayer

Over-application is a leading cause of turf damage. Calibrate your sprayer to deliver the correct rate specified on the product label. Use a dedicated sprayer for herbicides and never reuse it for other purposes without thorough cleaning. If you are using a granular product, use a spreader calibrated for the correct setting.

Watering After Application

Some products require watering after application to activate the herbicide, while others should be left dry for a period. Follow the label instructions exactly. Overwatering immediately after application can leach the product into the root zone and cause injury.

Spot Treat When Possible

For small weed infestations, spot treatment with a hand sprayer is safer than broadcasting herbicide over the entire lawn. This minimizes the total amount of chemical used and reduces the risk of turf injury. If you prefer a more targeted approach, consider using weeding tools for manual removal of small patches.

⚠️ Warning: Never use glyphosate (Roundup) or other non-selective herbicides on your St Augustine lawn. These products will kill your grass along with the weeds. If you must use glyphosate near your lawn, use a shielded applicator and apply on a calm day to prevent drift.

Common Weeds in St Augustine Lawns and How to Control Them

St Augustine lawns face a variety of weed pressures depending on region, season, and lawn health. Here are some of the most common weeds and the selective herbicide options that target them.

Broadleaf Weeds

Dandelions, clover, plantain, chickweed, and knotweed are common broadleaf weeds in St Augustine lawns. Three-way broadleaf herbicides containing 2,4-D, dicamba, and MCPP are effective against most of these weeds when applied according to label directions. For clover specifically, MCPP and dicamba are particularly effective.

Grassy Weeds

Crabgrass, goosegrass, and annual bluegrass can invade St Augustine lawns, especially in thin or stressed areas. Atrazine is effective against crabgrass and other annual grasses in St Augustine, but it must be applied before weeds emerge or when they are very small. Quinclorac can also control crabgrass, but only use products labeled for St Augustine and avoid application during hot weather.

Perennial Weeds

Weeds like nutsedge and pennywort can be challenging to control in St Augustine. Nutsedge requires specialized herbicides (like halosulfuron) that are safe for St Augustine but not always available to homeowners. Pennywort is a broadleaf weed that responds to three-way herbicides. For persistent perennial weeds, repeated applications may be necessary, and improving lawn health through proper fertilization and watering will help the grass outcompete weeds.

If you are also dealing with weeds in other areas, such as your vegetable garden, be sure to use a weed and grass killer safe for vegetable gardens to avoid contaminating your edible crops.

Preventing Weeds in St Augustine Grass

The best weed control is a healthy, dense lawn. St Augustine grass that is properly watered, fertilized, and mowed will naturally crowd out many weeds. Here are key preventive practices:

For more detailed guidance on maintaining a healthy lawn, explore our lawn care guides and learn about proper sprinkler systems to keep your grass consistently hydrated.

Frequently Asked Questions

What is the best weed killer that won't kill St Augustine grass?
The best options are selective post-emergent herbicides formulated with active ingredients like 2,4-D, dicamba, and MCPP (often combined in three-way products), or products containing atrazine where local regulations permit. Always confirm the label lists St Augustine grass as tolerant before applying.
Can I use Roundup on St Augustine grass?
No. Glyphosate (the active ingredient in original Roundup) is non-selective and will kill St Augustine grass along with the weeds. Only use glyphosate for spot treatment on weeds far from your lawn, or use a shielded applicator carefully.
When is the safest time to apply weed killer to St Augustine grass?
Apply when temperatures are between 65°F and 85°F, the grass is actively growing, and the lawn is not stressed by drought, disease, or recent mowing. Early morning or late afternoon application reduces evaporation and drift risk.
Will weed and feed products damage St Augustine grass?
Some weed and feed products can stress St Augustine, especially during hot weather or on newly established lawns. Choose a product specifically labeled for St Augustine, apply at the recommended rate, and water lightly after application unless the label says otherwise.
How long after applying weed killer can I mow my St Augustine lawn?
Wait at least 2 to 3 days after applying a selective herbicide before mowing. Mowing too soon can reduce the herbicide's effectiveness by removing treated foliage before the product is absorbed. Always check the product label for specific instructions.
Are there organic weed killers safe for St Augustine grass?
Organic options like vinegar and dish soap mixtures are non-selective and will damage St Augustine grass if sprayed directly. They are best used for spot treatment on weeds in cracks or far from desirable turf. For selective organic control, corn gluten meal can act as a pre-emergent, but results are less consistent than synthetic herbicides. If you prefer a DIY approach, learn about weed killer made with vinegar and Dawn dish soap, but use it cautiously around St Augustine.

Ready to Reclaim Your Lawn?

Browse our recommended selective herbicides and lawn care tools below to find the right products for your St Augustine grass. Always read labels and follow application instructions for safe, effective results.

Recommended Selective Weed Killers for St Augustine Grass

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Ortho WeedClear Lawn Weed Killer Ready-to-Use1 with Comfort Wand, 1 gal. | Weed Killer Spray, Kills Dollarweed, Dandelion, Clover and Chickweed, Won't Harm Lawn Grass When Used as Directed

Ortho WeedClear Lawn Weed Killer Ready-to-Use1 with Comfort Wand, 1 gal. | Weed Killer Spray, Kills Dollarweed, Dandelion, Clover and Chickweed, Won't Harm Lawn Grass When Used as Directed

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Ortho WeedClear Weed Killer for Lawns Ready-To-Spray, 32 fl. oz. | Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills Dandelion & Clover, Treats up to 16,000 sq. ft.

Ortho WeedClear Weed Killer for Lawns Ready-To-Spray, 32 fl. oz. | Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills Dandelion & Clover, Treats up to 16,000 sq. ft.

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Ortho WeedClear Weed Killer for Lawns Ready-to-Spray, 32 fl. oz. (2-Pack) | Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills Dandelion & Clover

Ortho WeedClear Weed Killer for Lawns Ready-to-Spray, 32 fl. oz. (2-Pack) | Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills Dandelion & Clover

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Ortho WeedClear Lawn Weed Killer Ready-to-Use1 Refill, 1 gal. | Weed Killer Spray, Kills Dollarweed, Dandelion, Clover and Chickweed, Won't Harm Lawn Grass When Used as Directed

Ortho WeedClear Lawn Weed Killer Ready-to-Use1 Refill, 1 gal. | Weed Killer Spray, Kills Dollarweed, Dandelion, Clover and Chickweed, Won't Harm Lawn Grass When Used as Directed

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Ortho WeedClear Weed Killer for Lawns Refill, 1 Gal. | Lawn Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills over 250 Listed Weeds Including Dandelion and Clover

Ortho WeedClear Weed Killer for Lawns Refill, 1 Gal. | Lawn Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills over 250 Listed Weeds Including Dandelion and Clover

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Ortho WeedClear Weed Killer for Lawns, Ready to Use, 1 gal. | Lawn Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills over 250 Listed Weeds Including Dandelion and Clover

Ortho WeedClear Weed Killer for Lawns, Ready to Use, 1 gal. | Lawn Weed Killer Spray, Won't Harm Grass When Used as Directed, Kills over 250 Listed Weeds Including Dandelion and Clover

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Ortho WeedClear Weed Killer for Lawns: Refill, Won't Harm Grass (When Used as Directed), Kills Dandelion & Clover, 1 gal. (Pack of 2)

Ortho WeedClear Weed Killer for Lawns: Refill, Won't Harm Grass (When Used as Directed), Kills Dandelion & Clover, 1 gal. (Pack of 2)

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Image Herbicide Crabgrass, Nutsedge, & Weed Killer for Lawns, 24 fl oz | Ready-to-Spray Weed Spray, Water Based Formula, for Established Lawns and Annual Grasses, Broadleaf Weeds, and Sedges

Image Herbicide Crabgrass, Nutsedge, & Weed Killer for Lawns, 24 fl oz | Ready-to-Spray Weed Spray, Water Based Formula, for Established Lawns and Annual Grasses, Broadleaf Weeds, and Sedges

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